The Alpha2move®

Innovation
Allyane

Alpha2move®: activate the motor zones by low-frequency sounds

2508-ALLYANE--9

By capitalizing on brain plasticity through the association of sounds generated by Alpha2move® with motor imagery work, the Allyane technique allows patients to regain their motor skills effectively and quickly.

This patented, non-invasive medical device is 100% made in France.

How does it work?

The Alpha2move® produces different sequences of low-frequency sounds with the aim of:
to activate the motor areas in the primary cortex.
to increase the action of motor imagery work.

Patented medical device

Explore Alpha2move
in 3D

Patient assessment and monitoring tool
Support for the session's proceedings
Personalized clinical monitoring dashboard
Exercise library
Regular updates (new features)

Effects of low-frequency sounds on brain plasticity*

Different auditory stimulations were compared, including some already recognized and used clinically. Analyses of brain power and connectivity show that the low-frequency sounds emitted by our medical device induce greater activation of motor regions, both in terms of connectivity and power.

This specific characteristic is what makes Allyane unique today.

* Dos Anjos T, Di Rienzo F, Benoit CE, Daligault S, Guillot A. Brain wave modulation and EEG power changes during auditory beats stimulation. Neuroscience. 2024 Jul 14;554:156-166. doi: 10.1016/j.neuroscience.2024.07.014. Epub ahead of print. PMID: 39004412.

DOI: 10.1016/j.neuroscience.2024.07.014

Neuromotor reprogramming: the fundamentals*

Correlations between performance and brain activity show that the addition of low-frequency sounds induces specific neuronal modulation, distinct from that observed with motor imagery alone, thus reinforcing the neurophysiological basis of neuromotor reprogramming.

*Typhanie Dos Anjos, Aymeric Guillot, Sebastien Daligault, Donna-Maria Chamoun, Thomas De Sousa, Franck Di Rienzo,
Low-frequency sounds combined with motor imagery elicits a transient disruption of force performance: A path to neuromotor reprogramming?

DOI: 10.1016 / j.neuroimage.2024.120746